Extent of RNA editing of glutamate receptor subunit GluR5 in different brain regions of the rat

@article{Paschen1994ExtentOR,
  title={Extent of RNA editing of glutamate receptor subunit GluR5 in different brain regions of the rat},
  author={Wulf Paschen and Bogdan Djuricic},
  journal={Cellular and Molecular Neurobiology},
  year={1994},
  volume={14},
  pages={259-270}
}
1. The structure and function of glutamate receptor subunits GluR2, GluR5, and GluR6 are changed by RNA editing. This reaction produces a base transition in the second transmembrane spanning region. The triplet CAG (coding for glutamine) is changed to CGG (coding for arginine). This transition has a pronounced effect on calcium fluxes through the respective ion channels, because calcium currents decrease with the rate of editing. 2. In the present study the extent of RNA editing of the… CONTINUE READING

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Generation and analysis of GluR5(Q636R) kainate receptor mutant mice.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1999
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References

Publications referenced by this paper.
Showing 1-10 of 15 references

Determinants of C a 2 + permeability in both TMI and TM 2 of high affinity kainate receptor channels : Diversity by RNA editing

N. Burnashev, B. Sakmann, P. H. Seeburg
Neuron • 1993

Determinants of C a 2+ permeability in both TMI and TM2 of high affinity kainate receptor channels: Diversity by RNA editing. Neuron 10:.491-500

M. K0hler, N. Burnashev, B. Sakmann, P. H. Seeburg
1993

RNA editing: exploring one mode with apolipoprotein B mRNA.

BioEssays : news and reviews in molecular, cellular and developmental biology • 1993

Structural determinants of ion flow through recombinant glutamate receptor channels

T. A. Verdoorn, N. Burnashev, H. Money, P. H. Seeburg, B. Sakmann
Science • 1991
View 1 Excerpt

glutamate receptor channels depends on subunit composition

R. I. Hume, R. Dingledine, S. F. Heinemann
1991
View 1 Excerpt

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