Extensive study of human insulin immunoassays: promises and pitfalls for insulin analogue detection and quantification.

@article{Heurtault2014ExtensiveSO,
  title={Extensive study of human insulin immunoassays: promises and pitfalls for insulin analogue detection and quantification.},
  author={B{\'e}atrice Heurtault and Nathalie Reix and N Meyer and Françoise Gasser and Marie-Jos{\'e}e Wendling and Charline Ratomponirina and Nathalie Jeandidier and R{\'e}my Sapin and Arnaud Agin},
  journal={Clinical chemistry and laboratory medicine},
  year={2014},
  volume={52 3},
  pages={355-62}
}
BACKGROUND Over the last few decades, new synthetic insulin analogues have been developed. Their measurement is of prime importance in the investigation of hypoglycaemia, but their quantification is hampered by variable cross-reactivity with many insulin assays. For clinical analysis, it has now become essential to know the potential cross-reactivity of analogues of interest. METHODS In this work, we performed an extensive study of insulin analogue cross-reactivity using numerous human… CONTINUE READING
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