Extensive reorganization of primary somatosensory cortex in chronic back pain patients

@article{Flor1997ExtensiveRO,
  title={Extensive reorganization of primary somatosensory cortex in chronic back pain patients},
  author={Herta Flor and Christoph Braun and Thomas Elbert and Niels Birbaumer},
  journal={Neuroscience Letters},
  year={1997},
  volume={224},
  pages={5-8}
}
The hypothesis of reorganization of the primary somatosensory cortex in states of chronic pain was assessed in 10 low back pain patients and nine matched healthy controls. [...] Key Method Intracutaneous electric stimuli were applied to the left back and index finger at a standard, a non-painful and a painful intensity. Magnetic fields were recorded by a 37-channel BTi biomagnetometer from the hemisphere contralateral to the site of stimulation. The power of the early evoked magnetic field (< 100 ms) elicited…Expand
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  • Applied psychophysiology and biofeedback
  • 2002
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It is shown that cortical plasticity related to chronic pain can be reduced by behavioral interventions that provide feedback to the brain areas that were altered by somatosensory pain memories. Expand
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Results suggest that chronic cervical radicular pain is associated with changes in neural activity at multiple levels of the somatosensory system, and the absence of correlation between the amplitude of spinal, brainstem, and cortical components of SEPs suggests that enhancement of cortical activity is not a simple amplification of subcortical enhancement. Expand
Mean sustained pain levels are linked to hemispherical side-to-side differences of primary somatosensory cortex in the complex regional pain syndrome I
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Patterns of cortical reorganization in complex regional pain syndrome
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This study showed reorganization of the S1 cortex contralateral to the CRPS affected side, and it appeared to be linked to complaints of neuropathic pain. Expand
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