Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosome

Abstract

Cytochrome P450 (CYP) 3A4 is a membrane protein that catalyzes hydroxylation of endogenous and exogenous substrates. Protein-protein interaction is a crucial factor that regulates the function of enzymes. However, protein-protein interactions involving human CYPs have not been fully understood. In this study, extensive protein-protein interactions involving… (More)
DOI: 10.1002/prp2.53

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