Extensive polymorphism of the FUT2 gene in an African (Xhosa) population of South Africa

@article{Liu1998ExtensivePO,
  title={Extensive polymorphism of the FUT2 gene in an African (Xhosa) population of South Africa},
  author={Yuhua Liu and Yoshiro Koda and Mikiko Soejima and Hao Pang and Terry Schlaphoff and Ernette D. du Toit and H. Kimura},
  journal={Human Genetics},
  year={1998},
  volume={103},
  pages={204-210}
}
The human secretor type α(1,2)fucosyltrans-ferase gene (FUT2) polymorphism was investigated in Xhosa and Caucasian populations of South Africa by polymerase chain reaction–restriction fragment length polymorphism and DNA sequencing. Six new base substitutions were found in the coding region of FUT2. A single base (C) deletion at nucleotide 778, which led to a frame shift and produced a stop codon at codon 275, was responsible for the enzyme inactivation. Three nonsynonymous base substitutions… Expand
Polymorphism of the human ABO‐Secretor locus (FUT2) in four populations in Asia: indication of distinct Asian subpopulations
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  • Clinica chimica acta; international journal of clinical chemistry
  • 2013
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