Extensive linkage disequilibrium in small human populations in Eurasia.

  title={Extensive linkage disequilibrium in small human populations in Eurasia.},
  author={Henrik Kaessmann and Sebastian Z{\"o}llner and Anna C Gustafsson and Victor Wiebe and M. ter Laan and Joakim Lundeberg and Mathias Uhl{\'e}n and Svante P{\"a}{\"a}bo},
  journal={American journal of human genetics},
  volume={70 3},
The extent of linkage disequilibrium (LD) was studied in two small food-gathering populations-Evenki and Saami-and two larger food-producing populations-Finns and Swedes-in northern Eurasia. In total, 50 single-nucleotide polymorphisms (SNPs) from five genes were genotyped using real-time pyrophosphate DNA sequencing, whereas 14 microsatellites were genotyped in two X-chromosomal regions. In addition, hypervariable region I of the mtDNA was sequenced to shed light on the demographic history of… CONTINUE READING