Extensive human DNA contamination in extracts from ancient dog bones and teeth.

@article{Malmstrm2005ExtensiveHD,
  title={Extensive human DNA contamination in extracts from ancient dog bones and teeth.},
  author={Helena Malmstr{\"o}m and Jan Stor{\aa} and Love Dal{\'e}n and Gunilla Holmlund and Anders G{\"o}therstr{\"o}m},
  journal={Molecular biology and evolution},
  year={2005},
  volume={22 10},
  pages={2040-7}
}
Ancient DNA (aDNA) sequences, especially those of human origin, are notoriously difficult to analyze due to molecular damage and exogenous DNA contamination. Relatively few systematic studies have focused on this problem. Here we investigate the extent and origin of human DNA contamination in the most frequently used sources for aDNA studies, that is, bones and teeth from museum collections. To distinguish contaminant DNA from authentic DNA we extracted DNA from dog (Canis familiaris) specimens… CONTINUE READING