Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis.


Copy number variants (CNVs) represent a substantial source of genomic variation in vertebrates and have been associated with numerous human diseases. Despite this, the extent of CNVs in the zebrafish, an important model for human disease, remains unknown. Using 80 zebrafish genomes, representing three commonly used laboratory strains and one native… (More)
DOI: 10.1073/pnas.1112163109


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