Extensive functional overlap between σ factors in Escherichia coli

Abstract

Bacterial core RNA polymerase (RNAP) must associate with a σ factor to recognize promoter sequences. Escherichia coli encodes seven σ factors, each believed to be specific for a largely distinct subset of promoters. Using microarrays representing the entire E. coli genome, we identify 87 in vivo targets of σ32, the heat-shock σ factor, and estimate that… (More)
DOI: 10.1038/nsmb1130

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@article{Wade2006ExtensiveFO, title={Extensive functional overlap between σ factors in Escherichia coli}, author={Joseph T. Wade and Daniel Castro Roa and David C. Grainger and Douglas Hurd and Stephen J. W. Busby and K. Struhl and Evgeny Nudler}, journal={Nature Structural &Molecular Biology}, year={2006}, volume={13}, pages={806-814} }