Extensive conformational sampling in a ternary electron transfer complex

@article{Leys2003ExtensiveCS,
  title={Extensive conformational sampling in a ternary electron transfer complex},
  author={David Leys and Jaswir Basran and François Talfournier and Michael J. Sutcliffe and Nigel S. Scrutton},
  journal={Nature Structural Biology},
  year={2003},
  volume={10},
  pages={219-225}
}
Here we report the crystal structures of a ternary electron transfer complex showing extensive motion at the protein interface. This physiological complex comprises the iron-sulfur flavoprotein trimethylamine dehydrogenase and electron transferring flavoprotein (ETF) from Methylophilus methylotrophus. In addition, we report the crystal structure of free ETF. In the complex, electron density for the FAD domain of ETF is absent, indicating high mobility. Positions for the FAD domain are revealed… CONTINUE READING
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