Extensive brain calcifications, leukodystrophy, and formation of parenchymal cysts: a new progressive disorder due to diffuse cerebral microangiopathy.

@article{Labrune1996ExtensiveBC,
  title={Extensive brain calcifications, leukodystrophy, and formation of parenchymal cysts: a new progressive disorder due to diffuse cerebral microangiopathy.},
  author={Philippe Labrune and Catherine Lacroix and Françoise Gouti{\`e}res and Jocelyne de Laveaucoupet and Philippe Chevalier and M Zerah and B{\'e}atrice Husson and Pierre Georges Landrieu},
  journal={Neurology},
  year={1996},
  volume={46 5},
  pages={
          1297-301
        }
}
A new cerebral disorder, described in three unrelated children, has recognizable clinical, radiologic, and neuropathologic findings. The onset occurs from early infancy to adolescence with slowing of cognitive performance, rare convulsive seizures, and a mixture of extrapyramidal, cerebellar, and pyramidal signs. CT shows progressive calcifications in the basal and cerebellar gray nuclei and the central white matter. MRI reveals diffuse abnormal signals of the white matter on T2-weighted… CONTINUE READING
Highly Cited
This paper has 72 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 37 extracted citations

Leukoencephalopathy, Cerebral Calcifications, and Cysts

AJNR. American journal of neuroradiology • 2006
View 11 Excerpts
Highly Influenced

Molecular basis of the human ribosomopathy Shwachman-Diamond syndrome.

Advances in biological regulation • 2018
View 1 Excerpt

Brain Calcification and Movement Disorders.

Current neurology and neuroscience reports • 2017

73 Citations

01020'01'04'08'12'16
Citations per Year
Semantic Scholar estimates that this publication has 73 citations based on the available data.

See our FAQ for additional information.