Extensive areas of aneuploidy are present in the respiratory epithelium of lung cancer patients.


According to the field cancerisation theory the entire upper aerodigestive tract has been mutagenised, thereby placing the affected individual at risk for the development of one or more cancers. To investigate this concept we studied the respiratory epithelium in lungs bearing cancer, including bronchi, bronchioles and alveoli. After identifying… (More)
DOI: 10.1038/bjc.1996.36


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