Extensive Distribution of Liposomes in Rodent Brains and Brain Tumors Following Convection-Enhanced Delivery

Abstract

Liposomes labeled with various markers were subjected to local–regional administration with either direct injection or convection-enhanced delivery (CED) into rodent brains and brain tumor models. Direct injection of liposomes containing attached or encapsulated fluorochromes and/or encapsulated gold particles indicated that tissue localization of liposomes… (More)
DOI: 10.1023/B:NEON.0000024743.56415.4b

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