Extensions to pedigree analysis. III. Variance components by the scoring method.

Abstract

The classic variance components for simple polygenic traits - additive, dominance, and environmental variance - have traditionally been estimated from sample covariances between first-degree relatives. If data is gathered on pedigrees, this statistical procedure wastes information. Recently Elston & Stewart suggested an alternative likelihood procedure that… (More)

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Cite this paper

@article{Lange1976ExtensionsTP, title={Extensions to pedigree analysis. III. Variance components by the scoring method.}, author={Ken Lange and Joseph Westlake and M. Anne Spence}, journal={Annals of human genetics}, year={1976}, volume={39 4}, pages={485-91} }