Extensional flow of hyaluronic acid solutions in an optimized microfluidic cross-slot device.

@article{Haward2013ExtensionalFO,
  title={Extensional flow of hyaluronic acid solutions in an optimized microfluidic cross-slot device.},
  author={Simon J Haward and Aditya Jaishankar and M{\'o}nica Oliveira and M A Alves and Gareth H. McKinley},
  journal={Biomicrofluidics},
  year={2013},
  volume={7 4},
  pages={044108}
}
We utilize a recently developed microfluidic device, the Optimized Shape Cross-slot Extensional Rheometer (OSCER), to study the elongational flow behavior and rheological properties of hyaluronic acid (HA) solutions representative of the synovial fluid (SF) found in the knee joint. The OSCER geometry is a stagnation point device that imposes a planar extensional flow with a homogenous extension rate over a significant length of the inlet and outlet channel axes. Due to the compressive nature of… CONTINUE READING