Extension of enzyme half-life during quiescence in Artemia embryos.

@article{Anchordoguy1993ExtensionOE,
  title={Extension of enzyme half-life during quiescence in Artemia embryos.},
  author={Thomas J. Anchordoguy and Gretchen E. Hofmann and Steven C Hand},
  journal={The American journal of physiology},
  year={1993},
  volume={264 1 Pt 2},
  pages={
          R85-9
        }
}
Encysted gastrulae of Artemia franciscana are known to enter a reversible state of quiescence in which biosynthetic and catabolic pathways are markedly suppressed. Given that these embryos can survive months of anoxia, we investigated their ability to extend the half-life of cytochrome-c oxidase (COX), a key metabolic enzyme, during anoxia. We calculate that the half-life of COX is extended to 101 days under anoxia, an estimated 77-fold increase compared with aerobic values. During conditions… CONTINUE READING
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