Extended use of topical nasal decongestants.

  title={Extended use of topical nasal decongestants.},
  author={Jung Kenn Yoo and Hadi R Seikaly and Karen H. Calhoun},
  journal={The Laryngoscope},
  volume={107 1},
Use of sympathomimetic topical nasal decongestants to treat nasal obstruction is usually restricted to 3 to 5 days to avoid potential rebound swelling (rhinitis medicamentosa). In this study, 10 healthy volunteers used oxymetazoline (long-acting topical nasal decongestant) nightly for 4 weeks. Subjects who used antihistamines, oral or topical decongestants, or systemic steroids or who had active sinusitis were excluded from the study. Weekly history, physical examination, and anterior… CONTINUE READING