Extended routine polymerase chain reaction surveillance and pre-emptive antiviral therapy for cytomegalovirus after allogeneic transplantation.

@article{Peggs2000ExtendedRP,
  title={Extended routine polymerase chain reaction surveillance and pre-emptive antiviral therapy for cytomegalovirus after allogeneic transplantation.},
  author={Karl S. Peggs and Wolfgang Preiser and Panagiotis D. Kottaridis and N Mckeag and Nicola S Brink and Richard S. Tedder and Anthony H. Goldstone and David Christopher Linch and Stephen Mackinnon},
  journal={British journal of haematology},
  year={2000},
  volume={111 3},
  pages={782-90}
}
Pre-emptive treatment strategies based on sensitive screening for cytomegalovirus (CMV) infection up to day +100 after allogeneic transplantation have been shown to reduce the incidence of CMV disease during the period of surveillance. However, the use of ganciclovir has been associated with delays in immune reconstitution and an increased incidence of late CMV disease after day +100. In the present study, 81 patients undergoing allogeneic transplantation received polymerase chain reaction (PCR… CONTINUE READING

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