Extended-release quetiapine as monotherapy for the treatment of adults with acute mania: a randomized, double-blind, 3-week trial.

@article{Cutler2011ExtendedreleaseQA,
  title={Extended-release quetiapine as monotherapy for the treatment of adults with acute mania: a randomized, double-blind, 3-week trial.},
  author={Andrew J. Cutler and Catherine J. Datto and Arvid Nordenhem and Margaret C. Minkwitz and Larisa Acevedo and Denis F Darko},
  journal={Clinical therapeutics},
  year={2011},
  volume={33 11},
  pages={1643-58}
}
BACKGROUND Bipolar disorder, a highly recurrent and chronic condition, often necessitates periods of hospitalization and requires lifelong treatment with medication. It is characterized by alternating episodes of mania and depression. Given the severity of mania, physicians must be able to control symptoms rapidly. OBJECTIVE The purpose of this pivotal, Phase III trial was to evaluate the efficacy and tolerability of once-daily extended-release quetiapine fumarate (quetiapine XR) monotherapy… CONTINUE READING

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References

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Showing 1-10 of 42 references

Efficacy of antimanic treatments : meta - analysis of randomized , controlled trials

  • RC Young, JT Biggs, VE Ziegler, DA Meyer
  • Neuropsychopharmacology
  • 2011

A double - blind , placebo - controlled study of quetiapine and lithium monotherapy in adults in the acute phase of bipolar depression ( EMBOLDEN I )

  • SL McElroy, RH Weisler, W Chang
  • 2010

A double - blind , placebo - controlled study of quetiapine and paroxetine as monotherapy in adults with bipolar depression ( EMBOLDEN II )

  • C Figueroa, M Brecher, JE Hamer-Maansson, H Winter
  • J Clin Psychiatry
  • 2010

Effectiveness of the extended release formulation of quetiapine as monotherapy for the treatment of acute bipolar depression

  • A Yildiz, E Vieta, S Leucht, RJ Baldessarini
  • J Affect Disord
  • 2010

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