Extended lymphadenectomy versus conventional surgery for rectal cancer: a meta-analysis.

  title={Extended lymphadenectomy versus conventional surgery for rectal cancer: a meta-analysis.},
  author={Panagiotis A. Georgiou and Emile Tan and Nikolaos Gouvas and Anthony Antoniou and G. S. Brown and Ralph John Nicholls and Paris P. Tekkis},
  journal={The Lancet. Oncology},
  volume={10 11},
BACKGROUND Lateral pelvic lymph-node metastases occur in 10-25% of patients with rectal cancer, and are associated with higher local recurrence and reduced survival rates. A meta-analysis was undertaken to assess the value of extended lateral pelvic lymphadenectomy in the operative management of rectal cancer. METHODS We searched Medline, Embase, Ovid, Cochrane Library, and Google Scholar for studies published between 1965 and 2009 that compared extended lymphadenectomy (EL) with standard… CONTINUE READING


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The Newcastle–Ottawa Scale (NOS) for assessing the quality of non randomised studies in meta-analyses

GA Wells, B Shea, D O’Connell
http://www.ohri.ca/programs/clinical_epidemiology/ oxford.htm (accessed Sept 15, • 2009

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