Extended lung cancer incidence follow-up in the Mayo Lung Project and overdiagnosis.

@article{Marcus2006ExtendedLC,
  title={Extended lung cancer incidence follow-up in the Mayo Lung Project and overdiagnosis.},
  author={Pamela M. Marcus and Erik J. Bergstralh and Mark H. Zweig and Ann Harris and Kenneth P. Offord and Robert S Fontana},
  journal={Journal of the National Cancer Institute},
  year={2006},
  volume={98 11},
  pages={748-56}
}
BACKGROUND A troubling aspect of cancer screening is the potential for overdiagnosis, i.e., detection of disease that, in the absence of screening, would never have been diagnosed. Overdiagnosis is of particular concern in lung cancer screening because newer screening modalities can identify small nodules of unknown clinical significance. Previously published analyses of data from the Mayo Lung Project, a large randomized controlled trial conducted among 9211 male cigarette smokers in the 1970s… CONTINUE READING
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