Extended longevity of wild-derived mice is associated with peroxidation-resistant membranes.

@article{Hulbert2006ExtendedLO,
  title={Extended longevity of wild-derived mice is associated with peroxidation-resistant membranes.},
  author={A. J. Hulbert and Sally C Faulks and James M. Harper and Richard L. Miller and Rochelle Buffenstein},
  journal={Mechanisms of ageing and development},
  year={2006},
  volume={127 8},
  pages={653-7}
}
Two lines of mice, Idaho (Id) and Majuro (Ma), both derived from wild-trapped progenitors, have previously been shown to have extended lifespans in captivity when compared to a genetically heterogenous laboratory line of mice (DC). We have examined whether membrane fatty composition varies with lifespan within the species Mus musculus in a similar manner to that previously demonstrated between mammal species. Muscle and liver phospholipids from these long-living mice lines have a reduced amount… CONTINUE READING

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