Extended high efficacy of the combination sulphadoxine-pyrimethamine with artesunate in children with uncomplicated falciparum malaria on the Benin coast, West Africa

Abstract

A study carried out in 2003–2005 in Southern Benin showed a day-28 sulphadoxine-pyrimethamine (SP) monotherapy failure rate greater than 40%, while for SP combined with artesunate (SP-AS) the failure rate was 5.3%. Such a large difference could be explained by the relatively short 28-day follow-up period, with a substantial number of recurrent infections… (More)
DOI: 10.1186/1475-2875-8-37

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Cite this paper

@article{Nahum2008ExtendedHE, title={Extended high efficacy of the combination sulphadoxine-pyrimethamine with artesunate in children with uncomplicated falciparum malaria on the Benin coast, West Africa}, author={Alain Nahum and Annette Erhart and Daniel Ahounou and D{\'e}sir{\'e} Bonou and Chantal van Overmeir and Joris Menten and Martin C. Akogb{\'e}to and Marc Coosemans and Achille Massougbodji and Umberto D'Alessandro}, journal={Malaria Journal}, year={2008}, volume={8}, pages={37 - 37} }