Extended flow cytometry characterization of normal bone marrow progenitor cells by simultaneous detection of aldehyde dehydrogenase and early hematopoietic antigens: implication for erythroid differentiation studies

@article{Mirabelli2007ExtendedFC,
  title={Extended flow cytometry characterization of normal bone marrow progenitor cells by simultaneous detection of aldehyde dehydrogenase and early hematopoietic antigens: implication for erythroid differentiation studies},
  author={Peppino Mirabelli and Rosa Di Noto and Catia Lo Pardo and Paolo Morabito and Giovanna Abate and Marisa Gorrese and Maddalena Raia and Caterina Pascariello and Giulia Scalia and Marica Gemei and Elisabetta Mariotti and Luigi del Vecchio},
  journal={BMC Physiology},
  year={2007},
  volume={8},
  pages={13 - 13}
}
Aldehyde dehydrogenase (ALDH) is a cytosolic enzyme highly expressed in hematopoietic precursors from cord blood and granulocyte-colony stimulating factor mobilized peripheral blood, as well as in bone marrow from patients with acute myeloblastic leukemia. As regards human normal bone marrow, detailed characterization of ALDH+ cells has been addressed by one single study (Gentry et al, 2007). The goal of our work was to provide new information about the dissection of normal bone marrow… CONTINUE READING

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