Extended Thromboprophylaxis with Betrixaban in Acutely Ill Medical Patients.

@article{Cohen2016ExtendedTW,
  title={Extended Thromboprophylaxis with Betrixaban in Acutely Ill Medical Patients.},
  author={Alexander A. Cohen and Robert A. Harrington and Samuel Z. Goldhaber and Russell Douglas Hull and Brian L. Wiens and Alex Gold and Adrian F. Hernandez and C Michael Gibson},
  journal={The New England journal of medicine},
  year={2016},
  volume={375 6},
  pages={534-44}
}
BACKGROUND Patients with acute medical illnesses are at prolonged risk for venous thrombosis. However, the appropriate duration of thromboprophylaxis remains unknown. METHODS Patients who were hospitalized for acute medical illnesses were randomly assigned to receive subcutaneous enoxaparin (at a dose of 40 mg once daily) for 10±4 days plus oral betrixaban placebo for 35 to 42 days or subcutaneous enoxaparin placebo for 10±4 days plus oral betrixaban (at a dose of 80 mg once daily) for 35 to… CONTINUE READING
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