Extended Practice of a Motor Skill Is Associated with Reduced Metabolic Activity in M1

@inproceedings{Picard2013ExtendedPO,
  title={Extended Practice of a Motor Skill Is Associated with Reduced Metabolic Activity in M1},
  author={Nathalie Picard and Yoshiya Matsuzaka and Peter Strick},
  booktitle={Nature Neuroscience},
  year={2013}
}
How does long-term training and the development of motor skills modify the activity of the primary motor cortex (M1)? To address this issue, we trained monkeys for ∼1–6 years to perform visually guided and internally generated sequences of reaching movements. Then, we used [14C]2-deoxyglucose (2DG) uptake and single-neuron recording to measure metabolic and neuron activity in M1. After extended practice, we observed a profound reduction of metabolic activity in M1 for the performance of… CONTINUE READING
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