Extended Oral Antibiotic Prophylaxis in High-Risk Patients Substantially Reduces Primary Total Hip and Knee Arthroplasty 90-Day Infection Rate

@article{Inabathula2018ExtendedOA,
  title={Extended Oral Antibiotic Prophylaxis in High-Risk Patients Substantially Reduces Primary Total Hip and Knee Arthroplasty 90-Day Infection Rate},
  author={Avinash Inabathula and Julian E. Dilley and Mary Ziemba-Davis and Lucian C. Warth and Khalid A. Azzam and Philip H. Ireland and R. Michael Meneghini},
  journal={The Journal of Bone and Joint Surgery},
  year={2018},
  volume={100},
  pages={2103–2109}
}
Background: Total joint arthroplasty (TJA) episodic payment models shift risk and cost of periprosthetic joint infection (PJI) to surgeons and hospitals, causing some to avoid treating high-risk patients. Furthermore, there are little data to support optimization of host factors preoperatively to decrease PJI, and recent literature supports using extended antibiotic prophylaxis following reimplantation TJA. The purpose of this study was to evaluate whether extended oral antibiotic prophylaxis… 

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