Extended Anticoagulation for VTE: A Systematic Review and Meta-Analysis.

@article{Mai2019ExtendedAF,
  title={Extended Anticoagulation for VTE: A Systematic Review and Meta-Analysis.},
  author={Vicky Mai and Charles-Antoine Guay and Laurie Perreault and S{\'e}bastien Bonnet and Laurent Bertoletti and Yves Lacasse and Sabine Jardel and J C Lega and Steeve Provencher},
  journal={Chest},
  year={2019},
  volume={155 6},
  pages={
          1199-1216
        }
}
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18 Citations
Highly Influential Citations
1
Background Citations
4
Results Citations
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18 Citations

Comparative effectiveness of oral anticoagulants in venous thromboembolism: GARFIELD-VTE.

Direct oral anticoagulants versus standard anticoagulation in children treated for acute venous thromboembolism

TLDR
This is the first meta-analysis of randomized controlled trials that focuses on the efficacy outcomes and safety endpoints of DOACs compared with standard anticoagulation in pediatric VTE.

Direct oral anticoagulants in the treatment of acute venous thromboembolism in patients with obesity: A systematic review with meta-analysis.

DOAC compared to LMWH in the treatment of cancer related-venous thromboembolism: a systematic review and meta-analysis

TLDR
DOAC were non-inferior to LMWH in preventing CA-VTE recurrence, but were associated with an increased risk of MB and CRNMB, and the risk/benefit ratio for specific populations.

Twice- or Once-Daily Dosing of Direct Oral Anticoagulants, a systematic review and meta-analysis.

Individualised Risk Assessments for Recurrent Venous Thromboembolism: New Frontiers in the Era of Direct Oral Anticoagulants

TLDR
There is a need for an individualised, targeted approach for assessing the risk of VTE recurrence, especially in those patients in whom the balance between benefit and risk of long-term anticoagulation is not clear.

Comparison of Bleeding Risk Scores in Elderly Patients Receiving Extended Anticoagulation with Vitamin K Antagonists for Venous Thromboembolism.

TLDR
The predictive performance of most clinical bleeding risk scores does not appear to be sufficiently high to identify elderly patients with VTE who are at high risk of bleeding and who may therefore not be suitable candidates for extended anticoagulation.

Treatment for Pulmonary Embolism: Anticoagulation Selection and Duration

TLDR
Select patient populations at high risk for clinical failure or hemorrhagic events, including morbidly obese, frail, elderly, or severe kidney dysfunction require further investigation into the optimal anticoagulant therapy that balances safety and effectiveness.

Long-term treatment of venous thromboembolism.

TLDR
After PE, patients should have clinical surveillance for chronic thromboembolic pulmonary hypertension, with ventilation-perfusion scanning and echocardiography being the initial diagnostic tests if CTEPH is a concern.

Extending anticoagulation treatment for unprovoked venous thromboembolism

TLDR
Two recent systematic reviews have addressed uncertainties about extending anticoagulation beyond the usually recommended periods in patients with unprovoked venous thromboembolism, and the rate of recurrent VTE has been studied in a recent BMJ systematic review.

References

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TLDR
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