Extended Anticoagulation for VTE: A Systematic Review and Meta-Analysis.
@article{Mai2019ExtendedAF, title={Extended Anticoagulation for VTE: A Systematic Review and Meta-Analysis.}, author={Vicky Mai and Charles-Antoine Guay and Laurie Perreault and S{\'e}bastien Bonnet and Laurent Bertoletti and Yves Lacasse and Sabine Jardel and J C Lega and Steeve Provencher}, journal={Chest}, year={2019}, volume={155 6}, pages={ 1199-1216 } }
16 Citations
Comparative effectiveness of oral anticoagulants in venous thromboembolism: GARFIELD-VTE.
- MedicineThrombosis research
- 2020
Direct oral anticoagulants in the treatment of acute venous thromboembolism in patients with obesity: A systematic review with meta-analysis.
- Medicine, BiologyPharmacological research
- 2020
DOAC compared to LMWH in the treatment of cancer related-venous thromboembolism: a systematic review and meta-analysis
- Medicine, BiologyJournal of Thrombosis and Thrombolysis
- 2020
DOAC were non-inferior to LMWH in preventing CA-VTE recurrence, but were associated with an increased risk of MB and CRNMB, and the risk/benefit ratio for specific populations.
Twice- or Once-Daily Dosing of Direct Oral Anticoagulants, a systematic review and meta-analysis.
- MedicineThrombosis research
- 2020
Individualised Risk Assessments for Recurrent Venous Thromboembolism: New Frontiers in the Era of Direct Oral Anticoagulants
- Medicine
- 2021
There is a need for an individualised, targeted approach for assessing the risk of VTE recurrence, especially in those patients in whom the balance between benefit and risk of long-term anticoagulation is not clear.
Comparison of Bleeding Risk Scores in Elderly Patients Receiving Extended Anticoagulation with Vitamin K Antagonists for Venous Thromboembolism.
- MedicineThrombosis and haemostasis
- 2021
The predictive performance of most clinical bleeding risk scores does not appear to be sufficiently high to identify elderly patients with VTE who are at high risk of bleeding and who may therefore not be suitable candidates for extended anticoagulation.
Treatment for Pulmonary Embolism: Anticoagulation Selection and Duration
- Medicine
- 2020
Select patient populations at high risk for clinical failure or hemorrhagic events, including morbidly obese, frail, elderly, or severe kidney dysfunction require further investigation into the optimal anticoagulant therapy that balances safety and effectiveness.
Long-term treatment of venous thromboembolism.
- MedicineBlood
- 2020
After PE, patients should have clinical surveillance for chronic thromboembolic pulmonary hypertension, with ventilation-perfusion scanning and echocardiography being the initial diagnostic tests if CTEPH is a concern.
Diagnosis and Treatment of Lower Extremity Venous Thromboembolism: A Review.
- MedicineJAMA
- 2020
Direct oral anticoagulants are noninferior to warfarin with regard to efficacy and are associated with lower rates of bleeding, but costs limit use for some patients.
Extending anticoagulation treatment for unprovoked venous thromboembolism
- MedicineBMJ Evidence-Based Medicine
- 2019
Two recent systematic reviews have addressed uncertainties about extending anticoagulation beyond the usually recommended periods in patients with unprovoked venous thromboembolism, and the rate of recurrent VTE has been studied in a recent BMJ systematic review.
References
SHOWING 1-10 OF 49 REFERENCES
Safety and efficacy of direct oral anticoagulants compared to warfarin for extended treatment of venous thromboembolism -a systematic review and meta-analysis.
- MedicineThrombosis research
- 2015
The impact of bleeding complications in patients receiving target-specific oral anticoagulants: a systematic review and meta-analysis.
- MedicineBlood
- 2014
A systematic review and meta-analysis of phase-3 randomized controlled trials to assess the bleeding side effects of TSOACs compared with VKAs in patients with venous thromboembolism or atrial fibrillation found they are associated with less major bleeding, fatal bleeding, intracranial bleeding, clinically relevant nonmajor bleeding, and total bleeding.
Comparative efficacy and safety of anticoagulants and aspirin for extended treatment of venous thromboembolism: A network meta-analysis.
- MedicineThrombosis research
- 2015
Direct oral anticoagulants compared with vitamin K antagonists for acute venous thromboembolism: evidence from phase 3 trials.
- MedicineBlood
- 2014
The efficacy and safety of DOACs were consistent in patients with pulmonary embolism, deep venous thrombosis, a body weight ≥100 kg, moderate renal insufficiency, an age ≥75 years, and cancer.
Extended anticoagulation and mortality in venous thromboembolism. A meta-analysis of six randomized trials.
- MedicineThrombosis research
- 2016
Editor's Choice - efficacy and safety of the new oral anticoagulants dabigatran, rivaroxaban, apixaban, and edoxaban in the treatment and secondary prevention of venous thromboembolism: a systematic review and meta-analysis of phase III trials.
- MedicineEuropean journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
- 2014
Efficacy and safety outcomes of oral anticoagulants and antiplatelet drugs in the secondary prevention of venous thromboembolism: systematic review and network meta-analysis
- MedicineBMJ
- 2013
All oral anticoagulants and antiplatelet agents investigated in this analysis were associated with a reduced recurrence of venous thromboembolism compared with placebo or observation, although acetylsalicylic acid was associated with the lowest risk reduction.
Clinical and safety outcomes associated with treatment of acute venous thromboembolism: a systematic review and meta-analysis.
- MedicineJAMA
- 2014
Findings suggest that the UFH-vitamin K antagonist combination is associated with the least effective strategy and that rivaroxaban and apixaban may be associatedwith the lowest risk for bleeding.
Apixaban for extended treatment of venous thromboembolism.
- MedicineThe New England journal of medicine
- 2013
Extended anticoagulation with apixaban at either a treatment dose (5 mg) or a thromboprophylactic dose (2.5mg) reduced the risk of recurrent venous thromboembolism without increasing the rate of major bleeding.
Comparative risk of gastrointestinal bleeding with dabigatran, rivaroxaban, and warfarin: population based cohort study
- MedicineBMJ : British Medical Journal
- 2015
The risk of gastrointestinal bleeding related to novel oral anticoagulants was similar to that for warfarin, and caution should be used when prescribing novel oral anti-cancer drugs to older people, particularly those over 75 years of age.