Expressions of the CagA protein and CagA-signaling molecules predict Helicobacter pylori dependence of early-stage gastric DLBCL.

@article{Kuo2017ExpressionsOT,
  title={Expressions of the CagA protein and CagA-signaling molecules predict Helicobacter pylori dependence of early-stage gastric DLBCL.},
  author={Sung-Hsin Kuo and L T Chen and Chung-Hui Lin and K. H. Yeh and Chia-Tung Shun and Y. S. Tzeng and Jyh-ming Liou and Ming-Shiang Wu and Ping-Ning Hsu and Ann-Lii Cheng},
  journal={Blood},
  year={2017},
  volume={129 2},
  pages={
          188-198
        }
}
We previously reported that early-stage gastric diffuse large B-cell lymphomas (DLBCLs), including DLBCLs with mucosa-associated lymphoid tissue (DLBCL[MALT]) and without ("pure" DLBCL) the features of MALT lymphomas, can achieve long-term complete remission after frontline Helicobacter pylori (HP) eradication (HPE). We recently reported that expression of cytotoxin-associated gene A (CagA) and CagA-signaling molecules (phospho-Src homology-2 domain-containing phosphatase [p-SHP2] and phospho… CONTINUE READING
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