Expressions of caspase-14 in human middle ear cholesteatoma.


OBJECTIVES Cholesteatoma is characterized by an excessive proliferation and differentiation of keratinocytes with a progressive accumulation of keratin debris. Caspase-14 is a novel regulator of keratinocyte terminal differentiation. The purpose of this study was to investigate the expression patterns and localizations of caspase- 14 in cholesteatoma and in… (More)
DOI: 10.1097/MLG.0b013e3181671b4d