Expression via ERK-1 / 2 and Nuclear Factor-Mediated Vasoconstriction by Stimulation of Endothelin Type-B Receptor − Endothelin-1 Relaxin , a Pregnancy Hormone , Is a Functional Endothelin-1 Antagonist : Attenuation of Print

@inproceedings{Bartsch2002ExpressionVE,
  title={Expression via ERK-1 / 2 and Nuclear Factor-Mediated Vasoconstriction by Stimulation of Endothelin Type-B Receptor − Endothelin-1 Relaxin , a Pregnancy Hormone , Is a Functional Endothelin-1 Antagonist : Attenuation of Print},
  author={Cornelia Bartsch and Christoph Richter and Michael Laule and Gert Baumann},
  year={2002}
}
We have recently demonstrated that relaxin (RLX) acts as compensatory mediator in human heart failure. RLX inhibits the stimulation of endothelin-1, the most potent vasoconstrictor in heart failure. Upregulation of the endothelin type-B receptor (ETB), which mediates endothelin-1 clearance and endothelial release of NO, represents a pivotal mode of RLX… CONTINUE READING