Expression profiling revealed keratins and interleukins as potential biomarkers in squamous cell carcinoma of horn in Indian bullocks (Bos indicus)

@article{Panchal2020ExpressionPR,
  title={Expression profiling revealed keratins and interleukins as potential biomarkers in squamous cell carcinoma of horn in Indian bullocks (Bos indicus)},
  author={Ketankumar J. Panchal and Prakash G. Koringa and Pritesh H. Sabara and Dhruv Bhatia and Subhash J. Jakhesara and Chaitanya G. Joshi},
  journal={3 Biotech},
  year={2020},
  volume={10}
}
Horn cancer is most prevalent in Bos indicus and poorly defined genetic landscape makes disease diagnosis and treatment difficult. In this study, RNA-Seq and data analysis using CLC Genomics Workbench was employed to identify biomarkers associated with horn cancer. As a result, a total of 149 genes were found significant differentially expressed in horn cancer samples compared to horn normal samples. The study revealed ‘keratins’ and ‘interleukins’ as apex groups of significant differentially… Expand
1 Citations
Genomics and transcriptomics in veterinary oncology
TLDR
Analysis of the literature indicated that employing genomic and transcriptomic technologies has been instrumental in developing the understanding of the origin, development and pathogenesis of several canine cancers, however, their use in canine oncology is at an early phase, and there appears to be comparatively little understanding of certain canine cancer types in contrast to their human forms. Expand

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