Expression profiling of supraglottic carcinoma: PTEN and thrombospondin 2 are associated with inhibition of lymphatic metastasis.

@article{Bai2009ExpressionPO,
  title={Expression profiling of supraglottic carcinoma: PTEN and thrombospondin 2 are associated with inhibition of lymphatic metastasis.},
  author={Wei-liang Bai and Liping Wang and Wenyue Ji and Hong Gao},
  journal={Acta oto-laryngologica},
  year={2009},
  volume={129 5},
  pages={
          569-74
        }
}
CONCLUSION Down-regulation of metastasis inhibitor genes PTEN and thrombospondin 2 may play a role in the lymphatic metastasis of supraglottic carcinoma. OBJECTIVES To investigate differentially expressed genes in supraglottic squamous cell carcinoma with and without lymphatic metastasis using cDNA microarray. MATERIALS AND METHODS cDNA microarray was used to detect the expression profiles of supraglottic carcinoma and the results were validated with real-time PCR. RESULTS Compared with… CONTINUE READING
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