Expression profiling of renal epithelial neoplasms: a method for tumor classification and discovery of diagnostic molecular markers.

@article{Young2001ExpressionPO,
  title={Expression profiling of renal epithelial neoplasms: a method for tumor classification and discovery of diagnostic molecular markers.},
  author={A N Young and Mahul B. Amin and Carlos S. Moreno and So Dug Lim and Cynthia K Cohen and John A. Petros and Fray F. Marshall and Andrew S. Neish},
  journal={The American journal of pathology},
  year={2001},
  volume={158 5},
  pages={1639-51}
}
The expression patterns of 7075 genes were analyzed in four conventional (clear cell) renal cell carcinomas (RCC), one chromophobe RCC, and two oncocytomas using cDNA microarrays. Expression profiles were compared among tumors using various clustering algorithms, thereby separating the tumors into two categories consistent with corresponding histopathological diagnoses. Specifically, conventional RCCs were distinguished from chromophobe RCC/oncocytomas based on large-scale gene expression… CONTINUE READING

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