Expression profiling of microdissected matched prostate cancer samples reveals CD166/MEMD and CD24 as new prognostic markers for patient survival.

@article{Kristiansen2005ExpressionPO,
  title={Expression profiling of microdissected matched prostate cancer samples reveals CD166/MEMD and CD24 as new prognostic markers for patient survival.},
  author={Glen Kristiansen and Christian Pilarsky and Christoph Wissmann and S. L{\"o}ffler Kaiser and Thomas Bruemmendorf and Stefan Roepcke and Edgar Dahl and Bernd Hinzmann and Thomas Specht and Janja Pervan and Carsten Stephan and Stefan Loening and Manfred Dietel and Andr{\'e} Rosenthal},
  journal={The Journal of pathology},
  year={2005},
  volume={205 3},
  pages={359-76}
}
In order to screen for differentially expressed genes that might be useful in diagnosis or therapy of prostate cancer we have used a custom made Affymetrix GeneChip containing 3950 cDNA fragments. Expression profiles were obtained from 42 matched pairs of mRNAs isolated from microdissected malignant and benign prostate tissues. Applying three different bioinformatic approaches to define differential gene expression, we found 277 differentially expressed genes, of which 98 were identified by all… CONTINUE READING