Expression profiling identifies novel Hh/Gli-regulated genes in developing zebrafish embryos.

@article{Bergeron2008ExpressionPI,
  title={Expression profiling identifies novel Hh/Gli-regulated genes in developing zebrafish embryos.},
  author={Sadie A. Bergeron and Luis A. Milla and Rosario Villegas and Meng-Chieh Shen and Shawn M. Burgess and Miguel L Allende and Rolf O. Karlstrom and Ver{\'o}nica Palma},
  journal={Genomics},
  year={2008},
  volume={91 2},
  pages={165-77}
}
The Hedgehog (Hh) signaling pathway plays critical instructional roles during embryonic development. Misregulation of Hh/Gli signaling is a major causative factor in human congenital disorders and in a variety of cancers. The zebrafish is a powerful genetic model for the study of Hh signaling during embryogenesis, as a large number of mutants that affect different components of the Hh/Gli signaling system have been identified. By performing global profiling of gene expression in different Hh… CONTINUE READING
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