Expression profiles of apoptotic genes induced by curcumin in human breast cancer and mammary epithelial cell lines.

@article{Ramachandran2005ExpressionPO,
  title={Expression profiles of apoptotic genes induced by curcumin in human breast cancer and mammary epithelial cell lines.},
  author={Cheppail Ramachandran and S. Fernando Rodriguez and Reshma Ramachandran and P K Raveendran Nair and Hugo B. Fonseca and Ziad El Khatib and Enrique A Escalon and Steven J. Melnick},
  journal={Anticancer research},
  year={2005},
  volume={25 5},
  pages={3293-302}
}
Curcumin (diferuloyl methane), the yellow-colored dietary pigment from the rhizomes of turmeric, has been recognized as a chemopreventive agent because of its antitumor, antioxidant and antiproliferative effects. The cytotoxic, apoptotic and gene regulatory effects of both turmeric and curcumin were investigated in the MCF-7 human breast cancer carcinoma cell line and compared with the effects in MCF-10A human mammary epithelial cells. MCF-7 cells were more sensitive to turmeric and curcumin… CONTINUE READING
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