Expression profile of hepatic genes related to lipid homeostasis in LSR heterozygous mice contributes to their increased response to high-fat diet.

@article{Akbar2016ExpressionPO,
  title={Expression profile of hepatic genes related to lipid homeostasis in LSR heterozygous mice contributes to their increased response to high-fat diet.},
  author={Samina Akbar and Anthony Pinçon and M C Lanhers and Thomas Claudepierre and Catherine Corbier and Lynn Gregory-Pauron and Catherine Malaplate-Armand and Athanase Visvikis and Thierry Oster and Frances T. Yen},
  journal={Physiological genomics},
  year={2016},
  volume={48 12},
  pages={
          928-935
        }
}
Perturbations of lipid homeostasis manifest as dyslipidemias and obesity, which are significant risk factors for atherosclerosis and diabetes. Lipoprotein receptors in the liver are key players in the regulation of lipid homeostasis, among which the hepatic lipolysis stimulated lipoprotein receptor, LSR, was recently shown to play an important role in the… CONTINUE READING