Expression profile of frizzled receptors in human medulloblastomas


Secreted WNT proteins signal through ten receptors of the frizzled (FZD) family. Because of the relevance of the WNT/β-catenin (CTNNB1) signaling pathway in medulloblastomas (MBs), we investigated the expression of all ten members of the FZD gene family (FZD1-10) in 17 human MBs, four MB cell lines and in normal human cerebellum, using real-time PCR. We… (More)
DOI: 10.1007/s11060-011-0682-6


5 Figures and Tables

Cite this paper

@article{Salsano2011ExpressionPO, title={Expression profile of frizzled receptors in human medulloblastomas}, author={Ettore Salsano and Rosina Paterra and Miriam Figus and Francesca Menghi and E Maderna and Bianca Pollo and Carlo Lazzaro Solero and Luca Massimi and Gaetano Finocchiaro}, journal={Journal of Neuro-Oncology}, year={2011}, volume={106}, pages={271-280} }