Expression profile of an androgen regulated prostate specific homeobox gene NKX3.1 in primary prostate cancer.

@article{Xu2000ExpressionPO,
  title={Expression profile of an androgen regulated prostate specific homeobox gene NKX3.1 in primary prostate cancer.},
  author={Linda L. Xu and Vasantha Srikantan and Isabell A. Sesterhenn and Meena Augustus and Rebecca A Dean and Judd W. Moul and Kenneth C. Carter and Sudhir Srivastava},
  journal={The Journal of urology},
  year={2000},
  volume={163 3},
  pages={972-9}
}
PURPOSE NKX3.1, a member of the family of homeobox genes, exhibits prostate tissue specific expression and appears to play a role in mouse prostate development. Rapid induction of NKX3.1 gene expression in response to androgens has also been described. On the basis of the established role of androgens in prostatic growth and differentiation and studies showing an association of aberrant homeobox gene expression with the neoplastic process, we hypothesize that alterations of NKX3.1 gene… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 41 extracted citations

Similar Papers

Loading similar papers…