Expression profile analysis of colon cancer cells in response to sulindac or aspirin.

@article{Iizaka2002ExpressionPA,
  title={Expression profile analysis of colon cancer cells in response to sulindac or aspirin.},
  author={Masayoshi Iizaka and Yoichi Furukawa and Tatsuhiko Tsunoda and Hirofumi Akashi and Michio Ogawa and Yusuke Nakamura},
  journal={Biochemical and biophysical research communications},
  year={2002},
  volume={292 2},
  pages={498-512}
}
Nonsteroidal anti-inflammatory drugs (NSAIDs) have a preventive effect against colorectal cancer. Although inhibition of cyclooxygenase-2 plays a crucial role in the suppression of tumors, precise mechanisms of their action remain to be disclosed. To identify genes involved in the growth-suppressive effect of NSAIDs, we utilized cDNA microarray containing 23,040 genes and analyzed time-dependent alteration of gene expression in response to sulindac or aspirin in NSAIDs-sensitive SW480 and SW948… CONTINUE READING

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