Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues.

@article{Choudhary2005ExpressionPO,
  title={Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues.},
  author={Dharamainder Choudhary and Ingela Jansson and Ivaylo Stoilov and Mansoor Sarfarazi and John B. Schenkman},
  journal={Archives of biochemistry and biophysics},
  year={2005},
  volume={436 1},
  pages={50-61}
}
The present study compared the relative expression pattern of 10 orthologous CYP forms from families 1-4 in cDNA panels of human and mouse fetal and adult tissues. Except for CYP1A2, all of these CYPs exhibited specific patterns of expression during mouse ontogeny, suggesting possible involvement in development. Cyp1a1 and Cyp2r1 were the only two of the orthologs to be expressed only in the E7 mouse; Cyp2s1 was expressed in all stages, including E7, while Cyp2e1 appeared only at E17. Highest… CONTINUE READING

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