Expression patterns of hormones, signaling molecules, and transcription factors during adenohypophysis development in the chick embryo.

@article{Parkinson2010ExpressionPO,
  title={Expression patterns of hormones, signaling molecules, and transcription factors during adenohypophysis development in the chick embryo.},
  author={Nicole Parkinson and Michelle M Collins and Lynn Dufresne and Aimee K. Ryan},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2010},
  volume={239 4},
  pages={1197-210}
}
The chick embryo is an ideal model to study pituitary cell-type differentiation. Previous studies describing the temporal appearance of differentiated pituitary cell types in the chick embryo are contradictory. To resolve these controversies, we used RT-PCR to define the temporal onset and in situ hybridization and immunohistochemistry to define the spatial localization of hormone expression within the pituitary. RT-PCR detected low levels of Fshbeta (gonadotropes) and Pomc (corticotropes… CONTINUE READING