Expression patterns of endogenous avian retrovirus ALVE1 and its response to infection with exogenous avian tumour viruses

@article{Hu2016ExpressionPO,
  title={Expression patterns of endogenous avian retrovirus ALVE1 and its response to infection with exogenous avian tumour viruses},
  author={Xuming Hu and Wenqi Zhu and Shihao Chen and Yangyang Liu and Zhen Sun and Tuoyu Geng and Chengyi Song and Bo Gao and Xiaoyan Wang and Aijian Qin and Hengmi Cui},
  journal={Archives of Virology},
  year={2016},
  volume={162},
  pages={89-101}
}
Endogenous retroviruses (ERVs) are genomic elements that are present in a wide range of vertebrates and have been implicated in a variety of human diseases, including cancer. However, the characteristic expression patterns of ERVs, particularly in virus-induced tumours, is not fully clear. DNA methylation was analysed by bisulfite pyrosequencing, and gene expression was analysed by RT-qPCR. In this study, we first found that the endogenous avian retrovirus ALVE1 was highly expressed in some… CONTINUE READING