Expression pattern of S100 calcium-binding proteins in human tumors.

@article{Ilg1996ExpressionPO,
  title={Expression pattern of S100 calcium-binding proteins in human tumors.},
  author={Evelyn C. Ilg and Beat W Sch{\"a}fer and Claus W. Heizmann},
  journal={International journal of cancer},
  year={1996},
  volume={68 3},
  pages={
          325-32
        }
}
The S100 Ca(2+)-binding proteins recently became of major interest because of their differential expression in neoplastic tissues, their involvement in metastatic processes, and the clustered organization of at least 10 S100 genes on human chromosome 1q21, a region frequently rearranged in several tumors. As a first attempt towards a specific and differentiated immunohistochemical classification of human tumors, we produced, purified and characterized a number of human recombinant S100 proteins… CONTINUE READING

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