Expression pattern and regulation of heme oxygenase-1/heat shock protein 32 in human liver cells.

@article{Bauer2003ExpressionPA,
  title={Expression pattern and regulation of heme oxygenase-1/heat shock protein 32 in human liver cells.},
  author={Inge Bauer and Hauke Rensing and Annekathrein Florax and Christoph Ulrich and Georg A. Pistorius and Heinz Redl and Michael Bauer},
  journal={Shock},
  year={2003},
  volume={20 2},
  pages={116-22}
}
Heme oxygenase-1 (HO-1) is a stress response protein that is highly inducible under various conditions, such as oxidative or heat stress. The present study investigated expression pattern and regulation of HO-1 in human liver. Expression pattern of HO-1 immunoreactive protein was studied in liver biopsies by immunohistochemistry, revealing constitutive expression in Kupffer cells but not in hepatocytes. HO-1 was, however, inducible in hepatocytes and vascular tissue under pathological… CONTINUE READING