Expression of xenobiotic metabolizing enzymes in breast cancer.

  title={Expression of xenobiotic metabolizing enzymes in breast cancer.},
  author={Graeme I. Murray and Richard J Weaver and P J Paterson and Stanley W. B. Ewen and William T. Melvin and M. Danny Burke},
  journal={The Journal of pathology},
  volume={169 3},
We have studied the expression of different xenobiotic metabolizing enzymes in primary operable breast cancer of no special type. The expression of two forms of cytochrome P450, microsomal epoxide hydrolase, and three classes of glutathione S-transferase was investigated using immunohistochemistry. The tumours were characterized by consistent expression of microsomal epoxide hydrolase and by variable expression of the two forms of cytochrome P450 and the three types of glutathione S-transferase… CONTINUE READING

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