Expression of very low density lipoprotein receptor mRNA in circulating human monocytes: its up-regulation by hypoxia.

@article{Nakazato2001ExpressionOV,
  title={Expression of very low density lipoprotein receptor mRNA in circulating human monocytes: its up-regulation by hypoxia.},
  author={Kazuhiko Nakazato and Toshiyuki Ishibashi and Kenji Nagata and Yutaka Seino and Youichiro Wada and Takayuki Sakamoto and Reiko Matsuoka and Tamio Teramoto and Masayuki Sekimata and Yasuhiko Homma and Yukio Maruyama},
  journal={Atherosclerosis},
  year={2001},
  volume={155 2},
  pages={439-44}
}
Although very low density lipoprotein (VLDL) receptor expression by macrophages has been shown in the vascular wall, it is not clear whether or not circulating monocytes express the VLDL receptor. We investigated the expression of VLDL receptor mRNA in human peripheral blood monocytes and monocyte-derived macrophages by reverse transcriptase polymerase chain reaction (RT-PCR) and nucleotide sequencing after subcloning of PCR product. VLDL receptor mRNA was detected both in peripheral blood… CONTINUE READING