Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in endometrial carcinoma.

@article{Guidi1996ExpressionOV,
  title={Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in endometrial carcinoma.},
  author={Anthony J. Guidi and Graziella M Abu-Jawdeh and Kathi Tognazzi and Harold F. Dvorak and Lawrence F. Brown},
  journal={Cancer},
  year={1996},
  volume={78 3},
  pages={454-60}
}
BACKGROUND Solid tumors, including endometrial carcinomas, must induce a vascular stroma to grow beyond a minimal size. The mechanisms responsible for angiogenesis in endometrial carcinoma, however, are not well defined. Vascular permeability factor (VPF), also known as vascular endothelial growth factor (VEGF), is a multifunctional cytokine that is an important regulator of tumor angiogenesis. We evaluated VPF/VEGF mRNA and protein expression, as well as VPF/VEGF receptor mRNA expression, in… CONTINUE READING