Expression of vascular endothelial growth factors and their receptors during osteoblast differentiation.

@article{Deckers2000ExpressionOV,
  title={Expression of vascular endothelial growth factors and their receptors during osteoblast differentiation.},
  author={Martine M. L. Deckers and Marcel Karperien and Chris van der Bent and Tetsuo Yamashita and Socrates E Papapoulos and Clemens W G M L{\"o}wik},
  journal={Endocrinology},
  year={2000},
  volume={141 5},
  pages={1667-74}
}
Endochondral bone formation is regulated by systemically and locally acting growth factors. A role for vascular endothelial growth factor (VEGF) in this process has recently been proposed, because inactivation of VEGF inhibits endochondral bone formation via inhibition of angiogenesis. Despite the known effect of VEGF as specific endothelial growth factor, its effects on osteoblast differentiation have not been studied. We, therefore, examined the expression of VEGF-A, -B, -C, and -D and their… CONTINUE READING
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